There's one that I go to on Tuesday nights- on weekends it's more a leather/denim and the crowd is mostly older.
On Tuesdays the crowd is mixed with everyone from guys that just turned 21 to cigar-smoking ladies in their 60s.
If I want to have a good time just chatting with a stranger and go somewhere where (almost) everyone knows my name- that's the place to go on a Tuesday night.