melanin) such as
Fonsecaea pedrosoi, Wangiella dermatitidis, etc.
- Chronic progressive granulomatous infection of skin and subcutaneous tissue, usually of
extremities.
- Mostly in Central and South America.
- Infection by direct implantation of organisms found in decaying vegetation.
- The raised, crusted, verrucous lesions involve a granulomatous host response to the fungus.
- Small, round, thick-walled, brown “sclerotic bodies” can be seen histopathologically.
VII. Lobomycosis, caused by
Loboa loboi (alternately, Lacazia loboi).
- Rare, slowly progressive infection of skin and subcutaneous tissue.
- Generally affects extremities, buttocks, face.
- Localized to Amazon region and other parts of Central and South America.
- Causative agent has not been cultured, but may be identified histopathologically as round
or oval cells in short chains in dermis.
- Genomic analyses indicate close relatedness to
Paracoccidioides brasiliensis.
- Also afflicts dolphins.
VIII. Rhinosporidiosis, caused by
Rhinosporidium seeberi.
- Chronic infection characterized by large nasal and other mucosal polyps.
- Localized to Asia, South America, and Africa.
- Causative agent has not been cultured, but may be identified histopathologically as
resembling an endosporulating fungus.
- Taxonomic classification has not been definitively established. Rather than a fungus, it
may be an aquatic protistan parasite, based on genomic analyses.
Wow- I'm really boring.
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