I love this thread and I'm going to repeat quite a few shows.
Buffy: (technically it wasn't cancelled though. UPN had a contract through the 7th season, so Joss Whedon (creator, producer, writer) knew ahead of time that unless Sarah (Michelle Geller) resigned that the 7th would be the last)
My So Called Life : I also loved this show!!!
Angel: I'm still mad at the WB for cancelling it. And what the heck was up with the series finale? What was that ending about?
Star Trek: TNG & Voyager: I gladly admit that I'm a huge trekkie. LOL. I was very sad when TNG went of the air and when UPN cancelled Voyager. Seven of Nine was cool on Voyager. LOL.
Felicity: Was I the only one who didn't like the ending?
Models Inc.: Wasn't the ending HORRIBLE!!! We still have no idea who was shot!!!!
Sisters: I loved the premise of this show. Plus, George Clooney was in it.
Sunset Beach: I know it's a soap opera, but I was saddened when it was cancelled. As soon as I got into it they cancelled it for Passions. But hey I like Passions, so I guess it's all good.
Lois & Clark: Dean Cain was just a hottie as Superman.