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Originally posted by HotDamnImAPhiMu
Wouldn't it have to make you more suceptible to ALL diseases, then? Because it'd be an immune system problem?
Fair enough.
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I am not sure, myself, EXACTLY what DEPO is... I will have to do a literature search to give you the references in PubMed...
But, I gather that Depo is liken to be a "specific" hormonal "replacement" drug that only interacts with specific receptors and target molecules within specific tissues--i.e. the pituitary and the ovaries...
So namely, the downstream signal transducers that get activated once depo binds its receptor class--more than likely the estrogen receptor family, somehow signals in the cells that causes other cells cells that are part of the "immune survellience" system to react. And these immune surveillance cells may be susceptible to "pre-existing" conditions--in the case of some chlamydia strains that are undetectible at low colony counts or in an new infection--like gonorrhea... It is unclear to me whether STI's are increased infection rates or the infections just became opportunistic...
However, I could be wrong. But the way I understand it, it is possible that there is some "mis-signalling" that is going on with these suceptible people that are out there--something to do with single nucleotide polymorphisms...
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