I tried to do this as a poll, but I can't figure out how and don't really feel like digging for it.
Hypothetically speaking: You're a young, single 20-something headed for the next phase of your life. There are places you are considering and each has it's own +/-. You don't know where you'd like to go, so you sit down and mull over the million dollar question:
New York City: Fun and fast-paced, you LOVE big cities. It would be the experience of a lifetime and you absolutely love all that it has to offer. With a roommate, you just might be able to avoid living in a carbboard box and you'd no longer need a car (goodbye high gas prices!). There's always something to do, the nightlife suits you, and you'll be in a new, exciting place you've always wanted to live in.
Atlanta: A wonderful place you've grown to feel at home in. Minimal family members around and maybe one or two friends, but you can always make more. You (generally) know the area and, though you're looking for something new, it'd be nice to live somewhere you're comfortable with. There's even a church you like. It's the cheapest option (seemingly) and the culture is something you adore.
Santa Barbara: Back to good ol' California, yet far enough away from the parental units that mom wouldn't be on the doorstep every other day. It's a high cost of living (but so's everywhere else) and a place you aren't the least bit familiar with, but all your family will be just a couple hours away and it's been YEARS since you've gotten to just call your cousins or sister up to go hang out. It'd be the best of both worlds.
So what would you choose? You don't have to say why, but it'd be nice.