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Last I heard is that there are 3 known strains of the virus... Most Americans and Europeans have strain A or B (I think, but have not read on the subject lately). Strain C is localized in Africa and some parts of Southeast Asia.
As far as a resistant strain of any of these viruses, it does not suprise me... The main culprit for mutating HIV RNA diploid strain is a highly unfaithful reverse transcriptase--no telling what crystal meth does to the very function of this protein...
Either way, the virus still enters into the CD4+ cells the same way and most of the cocktails only deal with AFTER HIV has entered the cell...
There are some drugs that do work on "entrance" but they are being considered the "vaccines"...
The problems is the very protein that is the "key" for entrance, is what gets changed every time the mutated reverse transcriptase fails to make this protein correctly--gp130 (they have other proteins that are involved, but I don't know them at this time).
Vaccination against HIV will be revolutionary in our current understanding of immunology--that's almost a guarentee from me... And it will be very unique--different from what has been done in the past...
But I NEVER get a straight answer from ANY scientist when I ask this question:
How come when someone has been diagnosed with AIDS and they do get some level of treatment, how come they don't also come down with all the secondary infections that they have been vaccinated against??? Like DPT, Measles, mumps, Rubella, Polio? Why? Should those bad ass illnesses crop up too?
NEVER heard a satifactory answer, YET...
I'm still waiting...
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