When I was fretting about weight gain once, my mom said something that put it all in perspective - "You didn't gain it all at once, so don't expect to lose it all at once"
I'm really wary of all the "diet supplements" ever since I had a bad experience with Metabolife. For the week I was on it, my heart would race and I was just waaaaay too sped up. And the 2 or 3 lbs I lost came right back when I stopped it.
I find that a Slim-Fast shake is a quick way to get a low-cal lunch when I'm in a rush - much much better for you than drive-thru. Also, I've found that Diet Mt. Dew, with all its caffeine speeds up my metabolism.
Although, brute force, i.e. exercise seems to be the best way to get weight off and keep it off.