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Vioxx questions
It is ironic when incomplete data gets turned around and someone high up in big pharma decides this is the way to go...
Vioxx is a cyclo-oxygenase 2 inhibitor (Coxibs). How it supresses pain in joints and arthritis is still under intense investigation. Celebrex and many of the NSAIDs do similar actions...
But all arthritis is not just inhibition of Cox2... There is more to it that just that... The chemical must be reacting with other enzymes causing severe stress on other organ systems, such as the heart, to cause infarction... That is being investigated, too.
Too bad for Merck... Just a few changes in their combinatorial chemistry and functional groups with a couple of more years in R&D may be would have saved them from all of this...
Merck is still pissed off with Pfizer for producing Viagra and pissed off with Eli Lilly for producing Prozac... Merck just is not the first one's to put stuff on the market since Mevacor--the cholesterol reducing drug... And Parke-Davis, bought out by Pfizer, makes the better product, Lipitor...
Big Pharma--not just for your health...
No wonder these new age nutriceuticals are big business...
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