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While working on inpatient psychiatric units for years, some bipolar patients expressed that they felt "bad" or "depressed" on their medications. We tried to work with them to help them realize that the high they felt when they were manic wasn't how most people feel all the time. If they were on a high for a long time, they often felt that "regular" was depressed. It was easier to keep them on meds when they swung to the depressed side, because that felt really awful to them. A lot of them were having a great time in their mania (although they were destroying their relationships, jobs, credit rating and engaging in a lot of dangerous behavior).
Dee
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