When I joined Kappa, there was an active sister who was in a wheelchair - I didn't know her all that well, as I was very shy the semester I pledged and didn't talk to a whole lot of people.
General attitude in the chapter towards her was just that we all liked her... she was really sweet. I know that she didn't live in the house because there were no bedrooms downstairs (except for the house mom's apartment) and so she really couldn't - she lived in a nearby dorm that was wheelchair accessible.
My chapter currently has an active disabled sister, she is not in a wheelchair but has limited mobility and walks with a limp. She does attend all chapter events, and lives in the house, and I've only had positive experiences with her.
I only went through one formal recruitment, and I can't remember coming across any disabled PNMs...