Similar to xo85xo's story....
This has to be in like 1st or 2nd grade.... running laps around the gym, and this one girl (I still remember her name!) bumped me to get me out of her way. Of course I fell over and skidded face first into the concrete wall. Broke my glasses, nearly broke my nose, and had two black eyes to show for it.
In high school....
We had single-sex gym, except for one unit... FOOTBALL! (Whose crazy idea was that?) I
hated gym, but I wanted to be "cool" for the boys, so I decided to play as hard as I could. The boys team had the ball, and I had a clear line towards the receiver. So I took off at top speed to "tackle" him (we were playing touch football, of course).... and the next thing I knew I was flying up in the air. When he went to block me, I was coming so fast that he overestimated the strength he'd need and flipped me up in the air with his block. I, of course, got knocked out cold, and the next thing I remembered was the whole gym class looking down at me, and the guy (who was by no means a star athlete himself) just saying "I am SOOOO sorry!"
He was really, really nice to me the rest of the year, though

And I'm pretty sure they don't play ANY co-ed sports anymore!