[AlphaSigOU]

Having been a former resident of Las Vegas, and also having my younger brother living and working there (he's dayshift 'boxman' (dice table supervisor) at the Palace Station hotel off the Strip) I tend to recommend accomodations off the Strip. They're usually less crowded, sometimes have lower table limits and are not overrun with tourists.

Rio - off the Strip but a very nice place.
The Palms - haven't been inside yet, but I'm told it's on par with or a little better than the Rio.
Gold Coast - mostly a locals joint.
Palace Station - caters mostly to locals, but gets a lot of traffic from interstate travel.
The Orleans - New Orleans-themed locals joint.

Way off the beaten path:

Texas Station - About as faux-Texan as Las Vegas can present, caters to locals
Fiesta - Another locals joint, Mexican themed.
Santa Fe Station - last major casino on US 95 before heading to the desert and the Nevada Test Site. Caters to locals, but also has a nice ice skating rink.
Sundance - Way out in the western foothills of Summerlin, caters to more upscale locals.
Sunset Station - caters to the local yuppies living in Green Valley.
Boulder Station - eastside locals joint.

BTW, in case you're wondering, I make it a rule never to play table games where my brother's working. There's no rule against it but you have to be discreet. Keeps the game honest.