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AstroAPhi,
I'll say as a rule of thumb, no more than 100% of the RDA (Recommened Daily Allowance). Toxicity varies from vitamin/mineral to vitamin/mineral. For example, anything above 100% RDA of iron is too much (unless your doctor says otherwise), on the other hand you can take megadoses of Vitamin B12 and it won't harm you that much. So you'll have to do some research.
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