Karen,
1. A duck tour
http://www.bostonducktours.com/.
2. walk the freedom trail (it is long, but worth it)
http://www.thefreedomtrail.org/
... those two will hit every historical site by land and sea in Boston.
4. RED SOX!!!!
3. Eat Italian in the North End... Mamma Maria, 3 North Square or Sage, 69 Prince St. both wonderful. There is a great pastry shop on Prince.. but I can not remember the name... I have to run to a Jr. League breakfast, but will PM it to you later.
4. Visit Faniel Hall and Quincy Market, they are both on the way to the North End. There is a club called The Rack
http://www.therackboston.com/, it has live music and is well known in Boston on Thursday and weekend nights for spotting sports celebrities.
5. Visit the top of the Prudential building, which is also where you pick up the Duck tour.
6. Go on a whale watching tour out of the harbor, next the Aquarium.
7. Shop Newbury street.
8. Within an hour outside of Boston you can go South to Quincy and visit President Adams' home. Or north to Salem and visit our infamous witching area.
9. Cambridge... Harvard and MIT
I know there is lots more... but I really must run. PM me and I will give you club details for the area you are staying in. Boston is called the Walking City... because you can just about walk everywhere.