There's a Hello Kitty store across from Madame Toussand's Wax Museum. My neice is a Hello Kitty fanatic and loves going there. The prices are very decent and includes products with all of the Hello Kitty characters. They even have Hello Kitty bubbble gum and candies.
On the same street as the wax museum there's a huge HMV, an Applebee's, and the Broadway show The Lion King. BB King's restaurant is on the same side of the street as the Hello Kitty store. It's the perfect place to experience the hustle-bustle of New Yorkers.
I can't wait to go to the new Toys R Us. My son has saved his Christmas/birthday/report card money so that he can go crazy there. Little does he know he's limited to two purchases. Anyway, he can't wait to see the ferris wheel and neither can I.
Also, don't forget about uptown. You can fish (need ID) at Central Park at 110th street ~ it's a catch and release program. There are activity kits available from the info. center there for a wide range of things you can do in the park. There's a nice garden somewhere in the mid/upper 90's where many people take their wedding pictures that you can walk to from 110th. There's also the El Barrio museum featuring Latino art/artists on 102nd (I think) street. All you have to do is walk down from the Park, no turning down avenues. NY is a great place for walking.
Further uptown, you can check out the Apollo Theater and Sylvia's restaurant. There's a wide variety of restaurants and great shopping there too. Lots of history...