By SPE, I assume you folks are saying Spee, not S P E? It has been more common in the south, but somtimes up here as well.
We used to call LCA "the Smurfs" because their house was painted blue with white trim. Years afterwards, still smurfs
Our (ADPhi) chapter at Johns Hopkins was known as WaWas after the store in the basement of the old chapter house. Most places we're known as AD or Alpha Delts, but at a few schools, we are known as the phis.