Quote:
Originally Posted by AKA_Monet
So what are WE all calling genetic manipulation? Series of brother sister matings somewhat like Mendel's "flowering pea pods"? Or are we talking insertion of DNA or shRNA or stablized microRNA fragments into the zygote/blastocyst stage to make transgenics or knockout dogs? Cloning dogs has not been proven to be overly difficult, some breeds, like Beagles are easy. Maybe pitbulls are similar? I don't know? 
But, I would not want to make transgenic pitbulls with anything added to them. A safer way to genetically modify them is injecting them with a disabled virus with an over-expression casette. |
Whether it's done under a microscope or supervised mating, it's still manipulation. Here is an article from the NYTimes about genetic manipulation on dogs as well as a bunch of other material it quotes:
"Free of most of the ethical concerns — and practical difficulties — associated with the practice of eugenics in humans, dog breeders are seizing on new genetic research to exert dominion over the canine gene pool. Companies with names like Vetgen and Healthgene have begun offering dozens of DNA tests to tailor the way dogs look, improve their health and, perhaps soon, enhance their athletic performance."
http://www.nytimes.com/2007/06/12/science/12dog.html
http://genetics.plosjournals.org/per...l.pgen.0030079
http://www.dogdna.org/
http://research.nhgri.nih.gov/dog_genome/
http://www.sciencemag.org/cgi/conten...t/316/5821/112
http://www.pnas.org/cgi/content/abstract/0506940103v1
http://jhered.oxfordjournals.org/cgi.../full/esm018v1
vetgen.com
genmarkag.com
healthgene.com
-Rudey
--There is nothing natural about creating Franken-dogs.