1) People who make rights on red and almost hit the pedestrians who have a walk signal
2) People who don't let my bus move over to the HOV lane - hello, the driver is trying to get OUT of your way
3) People.who.stop.look.listen. and then slooooowly make a right turn with no signal
4) People who tailgate me when I go 75 in a 55 because that is not fast enough for them
This city is notorious for the exit ramp situation ZTAngel described - luckily my car is tiny so I can go around them on the shoulder!

We also have awful awful tailgaters during rush hour - the other day I had to drive downtown instead of taking the bus and I was about to post a missed connection for the nice guy in the Lexus who didn't ride my ass the whole trip downtown!