Quote:
Originally posted by Gods Ivy
Sickle cell trait is not the same as having the disease and I think that is where folks are getting this case all mixed up. Just because you have the trait does not mean you feel any symptoms. If you produce a child and you and your mate have the trait then your child will have the disease. You can be a carrier of the trait and have not problems, due to distress or not. The issue is that they used excess force and continued to do so when the 14 year old's body went limp. Were you able to see the video. The nurse even watched as it happend.
|
As a Ph.D. in Molecular Genetics I am well aware of human hemaglobinapathies. One of which is Sickle Cell where the is a rearrangement of beta-globin gene locus with various haplotypes.
One of the many problems with human Beta-globinapathies are the haploinsufficiencies. That is what they mean by carriers of the the trait. Since the beta-globin gene locus is one of the largest ones and there is a switching of several exons during the development, at any point there could be problems that obtaining a fully functional hemaglobin as someone that may just carry the trait reaches puberty.
When scientists and medical doctor's say stress, it means, that when there is low oxygen tension in the lungs that causes the increases in blood pressure, hyperventilation, and perceived "flight or fight" responses that are activated under the parasympathetic nervous system. Since hemaglobin is an intricate part of that process and blood is rapidly moving everywhere to create some kind of response in the body, through the action of hormones, including thyroid and insulin, red blood cell sickling, because of an incomplete protein due to haploinsufficiency or compound heterozygosity can exacerbate a response with someone that merely carries the trait...
Moreover, there are other environmental external factors, aside from the hitting by personnel, such as substance abuse, or poor nutrition, that could make someone that carries the sickle cell trait more prone to certain pathologies: i.e. increased tumorigenesis, aneurysm [sp?] and stroke. How a thallesemia could cause all of these secondary chronic diseases are under intense investigation.
And what you have here is a developing adolescent with raging hormones and the personnel could care less of his medical condition. Already, that speaks volumes to the neurological conditions he has yet to fully manifest, if he develops them appropriately at all...